When starting out on a fresh design it’s a generally good idea to make sure that all browsers are going to react in the same way to your CSS coding.
I find Yahoo’s CSS Reset to be a useful tool to add to the start of a stylesheet but what happens when you want to reboot elements (like p’s, ul’s, ol’s etc.) that were reset? What were those browser defaults that were lost?
This forum posting on accessifyforum.com has a few pointers which I’ll put into a base stylesheet at some point in the future.
In the meantime I’m afraid you will have to judge for yourself…